April 4 - Hideo Nomo hurls a 3-0 no-hitter against the Orioles in his Boston debut. It is Nomo's second career no-hit no-run, making him the 4th pitcher in history to hurl one in both the National League and the American League. It is also the earliest no-hitter, by date, in history.
April 14 - A major league record is set as 11 one-run games are played, breaking the mark of 10 set in 1967. With a 1–0 win over the Mets, Cincinnati set the modern day National League record with their 175th consecutive game without being shutout, breaking the mark of 174, set by the 1992-93 Philadelphia Phillies.
May 5 - The Chicago Cubs defeat the Dodgers, 20-1. It was the 15th time since 1900 that Chicago have scored 20 runs in a game and the 11th time they've done it at Wrigley Field.
May 16 - Rickey Henderson leads off with a home run, extending his major-league record for leadoff home runs to 79. This more than twice the total for the #2 and #3 players on the list: Brady Anderson (44) and Bobby Bonds (35).
June 12 - Dodgers outfielderGary Sheffield became the first player in major league history to win three 1-0 games in a season with a home run, when he solos to beat the Atlanta Braves, 1-0. He also supplied the only scoring by homering in April 2, versus Milwaukee, and in May 7, against Florida.
Albert Pujols ties Emmet "Snags" Heidrick (1899) for most hits by a Cardinal rookie when he makes his 194th.
Barry Bonds extends his major-league record with his 73rd home run of the season. He will finish the year with a .863 slugging percentage to break Babe Ruth's all-time single-season record.
In a day of records, The Cubs lose to the Pirates in their final game of the season, 4-3. They become the first team in major league history to not allow an opposing pitcher to throw a complete game against them all season. Sammy Sosa closes out 2001 with his 64th homer in his final at-bat of the game and sets a new franchise record with 98 extra base hits, one more than Hack Wilson (1930). Sosa also finishes with another franchise record of 425 total bases (the 7th best all-time total), two ahead of Wilson. His 160 RBI is the highest total in the National League since Chuck Klein posted 170 in 1930; Sosa's RBI total for the past four years also breaks Klein's four-year mark set in 1929-32. To finish out the record day, five Cubs pitchers combine for 12 strikeouts as the staff sets a major league record with 1,246 strikeouts. The Yankees did the same, setting an American League mark with 1,266 strikeouts.
December 20 - The limited partners of the Red Sox vote unanimously to sell the team to a group led by Florida Marlins owner John Henry and former Padres owner Tom Werner . The $660 million price, plus an assumption of $40 in debt, would double the record price for a baseball team.
April 9 - Willie Stargell. 61, elected to the Baseball Hall of Fame in his first year of eligibilty, and a one of the most famous players in Pittsburgh Pirates history.
August 29 - Dick Selma , 57, a former pitcher for the Mets, Cubs, Phillies and San Diego Padres, who set a Mets' record with a 13-strikeout game, and was was the winning pitcher in the Padres' first win of their inaugural season.
September 17 - Bubba Church , 77, a pitcher for the Phillies' famed Whiz Kids, who also pitched with the Reds and Cubs.
October 5 - Woody Jensen , 94, an outfielder who played in nine seasons with the Pirates, and who set a record for leadoff hitters with 696 at-bats (1936).
October 18 - Ferris Fain , 80, a four-consecutive All-Star and a two-time batting champion, who played with the Philadelphia Athletics, Detroit, Cleveland and White Sox.
November 29 - Marcelino López , 58, who lost out on American League Rookie of the Year to the Oriole's Curt Blefary in 1965, and pitched with the Phillies, Orioles, Brewers and Indians.
