The ChiPitts megalopolis is the name for a group of metropolitan areas in the Mid-Atlantic and Midwest of the United States, extending from Pittsburgh to Chicago and linked by economics, transport, and communications. The geographic trend was first identified in the 1961 book Megalopolis: The Urbanized Northeastern Seaboard of the United States by French geographer Jean Gottman.

Gottman also envisaged the development of two similar megalopolises in the US: BosWash from Boston to Washington, DC and SanSan from San Francisco to San Diego.

The major cities in the ChiPitts megalopolis include the following:

• Pittsburgh, Pennsylvania
• Detroit, Michigan
• Cleveland, Ohio
• Columbus, Ohio
• Cincinnati, Ohio
• Indianapolis, Indiana
• Chicago, Illinois

ChiPitts also roughly has the same boundaries as the Rust Belt.