Hepburn can have a variety of meanings:

• Hepburn is the system used to transcribe the Japanese language into the Roman alphabet.
• Hepburn is a village in Victoria in Australia.
• Hepburn is a town in Saskatchewan in Canada.
• Hepburn Township is a town in Lycoming County, Pennsylvania in the United States.
• Hepburn was an all-female British pop band.
• Audrey Hepburn was an actress.
• Dee Hepburn was an actress.
• Doug Hepburn was a Canadian weightlifter.
• Katharine Hepburn was an actress.
• Rev. James Curtis Hepburn was a linguist.
• Stephen Hepburn is a British Member of Parliament.
• Hepburn is the name of a family of Scottish nobles:
  • Patrick Hepburn, 1st Lord of Hailes
  • Adam Hepburn, Master of Hailes (son of Patrick, 1st Lord of Hailes)
  • John Hepburn (son of Patrick, 1st Lord of Hailes)
  • Patrick Hepburn, 1st Earl of Bothwell (son of Adam, Master of Hailes)
  • Adam Hepburn of Craggis (son of Adam, Master of Hailes)
  • George Hepburn (son of Adam, Master of Hailes)
  • Adam Hepburn, 2nd Earl of Bothwell (son of Patrick, 1st Earl of Bothwell)
  • Patrick Hepburn, 3rd Earl of Bothwell (son of Adam, 2nd Earl of Bothwell)
  • James Hepburn, 4th Earl of Bothwell (son of Patrick, 3rd Earl of Bothwell) - lover and third husband of Queen Mary I of Scotland.
  • Francis Stewart Hepburn, 1st Earl of Bothwell (nephew of James, 4th Earl of Bothwell)