James Watson Cronin (born September 29, 1931) is an American nuclear physicist.

He was born in Chicago, Illinois. Cronin and co-researcher Val Logsdon Fitch were awarded the 1980 Nobel Prize in Physics for a 1964 experiment that proved that certain subatomic reactions do not adhere to fundamental symmetry principles. Specifically, they proved, by examining the decay of K-mesons, that a reaction run in reverse does not merely retrace the path of the original reaction, which showed that the reactions of subatomic particles are not indifferent to time.

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• James Watson Cronin