The stadium is perhaps better known by its now-infamous former name, Enron Field. Astros managers faced a public relations nightmare when the energy corporation went bankrupt in the midst of one of the biggest business scandals in American history in 2001, and they bought back the remainder of Enron's thirty years of naming rights, hastily rechristening the ballpark as "Astros Field". In 2002 Minute Maid, the fruit-juice subsidiary of Coca-Cola, acquired the naming rights to the stadium. Removing all of the signage that included the old Enron Field name proved a time-consuming and costly process.

The ballpark was Houston's first retractable-roofed stadium, thus enabling it to be hermetically sealed from hot or inclement weather like its predecessor, the Reliant Astrodome, or left open on more pleasant days. Its entrance is what was once Houston's Union Station, and one side of the stadium features a train as homage to the site's history. The train runs the length of the exterior wall beyond left field whenever an Astros player hits a home run.

During its days as Enron Field, it was also dubbed "Home Run" Field due to its cozy dimensions. Becoming the second major league ballpark named after citrus products (after Tropicana Field) seemed appropriate, since both the ball and the sluggers of this era have allegedly been "juiced".

The stadium is known for being particularly hitter-friendly down the lines, especially in left field, where it is only 315 ft. to the Crawford St. Boxes. Conversely, it is quite difficult to hit a ball out in center field, though fielding is quite difficult there as well, due to the fairly steep up-sloped grade, sometimes known as Tal's Hill, for team president Tal Smith, an element taken from Crosley Field and other historic ballparks, and the flagpole in play, an element taken from Tiger Stadium among others. The difference is that the Crosley Field "terrace" was necessitated by the difference in elevation between field level and street level. "Tal's Hill" is purely decorative. Both structures have been held in equal disdain by the respective outfielders that have had to patrol those areas.

Above Tal's Hill is a concourse known originally as the Crosley Field Terrace as another legacy to the old Crosley Field, however it is now known as "Home Run Alley" that includes the fan-favorite "Conoco Home Run Porch" in left-center field that is actually over the field of play, and features a classic gasoline pump to keep track of the number of Astros home runs that are hit.

In 2004, the Astros launched Wi-Fi throughout the ballpark, allowing fans to use the internet while attending a game.