Mona may mean:

• Mona, the Saxon moon deity
• Mona, a character from the cartoon The Simpsons
• the Roman name for the island of Anglesey
• the Isle of Man (in poetic language)
• Mona, a Shift-JIS art character in one of Japan's BBS's, 2-channel
• Mona, Jamaica , a town that is the site of one of the University of the West Indies campuses [1]
• Mona, Puerto Rico, an island in the Mona Passage between Puerto Rico and the Dominican Republic
• Mona, Utah, a town in the US
• Mona, character from WarioWare video game
• Mona, an operating system from Japan
• MoNA , an acronym that stands for Modified Nucleic Acid