Nicodemo Scarfo (born March 8, 1929) was a member of the US Mafia.

Nicknamed 'Little Nicky' due to his small stature (five-foot-six), Scarfo was regarded as a volatile and violent boss. Numerous informants claimed he was quite narcissistic, and would often scan the newspapers in the hope of seeing that he had been mentioned in any crime reports. This ran against the tradition of Mob Bosses as being shy of media attention, such as his predecessor, Angelo Bruno.

Scarfo established himself in Atlantic City in the 1970s then became boss of the Philadelphia Family after Angelo Bruno was murdered in 1980. Scarfo orchestrated a particularly ruthless regime. He had at least thirty members of his own crew murdered because they either refused to obey orders or were merely suspected of not being loyal enough. Scarfo was a cold-hearted killer that liked to go out with his soldiers and kill people even when his status as Boss did not require him too. His turncoat nephew Phil Leonetti claims that he murdered his wife's ex-lover who was bothering her, and in mid-shoot, exclaimed "I love killing people!"

His son, Nicky, Jr., was almost murdered on Halloween, 1989 in an Italian restaruant, by a rival gang leader from Detroit, Gaspare Arcilesi. Fearing another Mafia war, he got him out of town and inducted him into the Lucchese Family of New York for protection. That same year, he was imprisoned for six months for parole violation for having a gun. While in prison, he was indicted for RICO and the murder of a suspected informant.

Scarfo was sentenced to life imprisonment at Supermax , primarily on the testimony of a number of informants, including his nephew. He managed to overturn his life sentence and get transferred to a FCI in Atlanta, Georgia, where he resides with famous prisoners such as Mutulu Shakur.

Scarfo is scheduled for release in 2033 when, assuming he lives that long, he will be 104.