Poindexter is a character in the fictional Felix the Cat universe. He is the young nephew of the Professor, the arch-nemesis of Felix.

Poindexter is depicted as a stereotypical scientist; he is very intelligent and always wears thick glasses, a lab coat, and a mortarboard. A button on the chest of his lab coat acts as a control for whatever device the plot calls for. He helps his bumbling uncle concoct elaborate schemes to get Felix and capture his Magic Bag, though at times both are depicted as Felix's friends.

Introduced with the creation of a Felix the Cat television cartoon series in 1958, the character proved to be very popular; so much so that today the term "Poindexter" is applied to people who are overly nerdy or bookish. As a nod to this usage, one of the characters from the movie Revenge of the Nerds (and its sequels) was given this name.

Or John Poindexter - National Security Advisor during the Ronald Reagan presidency.

Or Poindexter Online - a journal of undergraduate work.