River Derwent is the name of several rivers in England:

• River Derwent, Derbyshire; see also Derwent Reservoir, Derbyshire, also Upper Derwent Valley.
• River Derwent, North East England on the border between County Durham and Northumberland; see also: Derwent Reservoir, North East England.
• River Derwent, Cumbria in the Lake District; see also Derwent Water.
• River Derwent, Yorkshire in Yorkshire

The name "Derwent" means "a valley thick with oaks". The Romans had an encampment called Derventio on the banks of the Derwent at what is now Derby (Derby, England). The Roman spelling was Darwent. The Derwent Reservoir is located at the Derwent Valley, downstream of the Howden Reservoir. The river flows on through Derby.

The Derwent River, Tasmania was named after one of the River Derwents.