The Sabine River is in the South Island of New Zealand.

The headwaters are in the Nelson Lakes National Park. The river drains Lake Constance and the Blue Lake and flows into Lake Rotoroa. Apart from the upper reaches, which is open tussock and scrub, the river is set within unmodified beech forest. It is not a navigable river due to the rocky cascades along most of its length.

A tramping track runs along the river and forms part of the Travers-Sabine tramping circuit.