There is more than one Treaty of Madrid:

• Treaty of Madrid (1526) , in which France renounced claims in Italy, surrendered Burgundy to Spain, and abandoned suzerainty over Flanders and Artois
• Treaty of Madrid (1670), in which Spain recognized British possessions in the Caribbean Sea, such as Jamaica and the Cayman Islands
• Treaty of Madrid (1750), which supplemented the Treaty of Aix-la-Chapelle between Spain and Great Britain
• Treaty of Madrid (1795), (also known as Pinckney's Treaty or the Treaty of San Lorenzo) settling boundaries between the United States and Spain